The DNA Profile Database Oversight Board is an independent administrative body with powers of authority answerable only to the Assembly of the Republic. It was created by Law no. 5/2008 of 12 February 2008 to oversee the DNA profile database.

Law no. 40/2013 of 25 June 2013 regulates how the Board is organised and how it functions as well as the personal status of its members.
The oversight board controls the DNA profile database, notwithstanding the oversight authority of the Assembly of the Republic, applying its competences as listed in article 2 of Law no. 40/2013 of 25 June 2013 and Law no. 5/2008 of 12 February 2008.​